The emergence of resistant pneumococcal meningitis--implications for empiric therapy
نویسندگان
چکیده
منابع مشابه
The emergence of resistant pneumococcal meningitis--implications for empiric therapy.
BACKGROUND Following the emergence of penicillin and cephalosporin resistant pneumococcal meningitis in the United States, inclusion of vancomycin in empiric therapy for all suspected bacterial meningitis was recommended by the American Academy of Pediatrics. Few data are available to evaluate this policy. AIMS To examine the management and clinical course in relation to antibiotic therapy of...
متن کاملClinical outcome of pneumococcal meningitis during the emergence of pencillin-resistant Streptococcus pneumoniae: an observational study
BACKGROUND Prior to the availability of generic third-generation cephalosporins, penicillins were widely used for treatment of pneumococcal meningitis in developing countries despite concerns about rising levels of penicillin resistance among pneumococcal isolates. We examined the impact of penicillin resistance on outcomes of pneumococcal meningitis over a ten year period in an infectious dise...
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1. In experimental Type I pneumococcal meningitis of dogs central cord involvement is common after the 2nd day of the disease. 2. These central cord lesions may progress toward extensive suppurative myelitis. 3. Abscesses are infrequent; they arise either as direct perivascular extensions of the meningeal disease or at the site of infected purpuric lesions. 4. In prolonged untreated meningitis ...
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چکیده ندارد.
15 صفحه اولExperimental study of LY333328 (oritavancin), alone and in combination, in therapy of cephalosporin-resistant pneumococcal meningitis.
Using a rabbit model of meningitis, we sought to determine the efficacy of LY333328, a semisynthetic glycopeptide, in the treatment of cephalosporin-resistant pneumococcal meningitis. LY333328 was administered at a dose of 10 mg/kg of body weight/day, alone and in combination with ceftriaxone at 100 mg/kg/day with or without dexamethasone at 0.25 mg/kg/day. The therapeutic groups were treated w...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 2002
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.87.3.207